Cardiotoxic Effects of Short-Term Doxorubicin Administration: Involvement of Connexin 43 in Calcium Impairment

The use of Doxorubicin (DOXO), a potent antineoplastic agent, is limited by the development of cardiotoxicity. DOXO-induced cardiotoxicity is multifactorial, although alterations in calcium homeostasis, seem to be involved. Since even the Connexin43 (Cx43) plays a pivotal role in these two phenomena...

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Detalles Bibliográficos
Autores principales: Pecoraro, Michela, Rodríguez-Sinovas, Antonio, Marzocco, Stefania, Ciccarelli, Michele, Iaccarino, Guido, Pinto, Aldo, Popolo, Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666803/
https://www.ncbi.nlm.nih.gov/pubmed/29019935
http://dx.doi.org/10.3390/ijms18102121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666803/
https://www.ncbi.nlm.nih.gov/pubmed/29019935
http://dx.doi.org/10.3390/ijms18102121

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