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ASIC1a Promotes Acid-Induced Autophagy in Rat Articular Chondrocytes through the AMPK/FoxO3a Pathway

Acid-sensing ion channel 1a (ASIC1a) is a member of the extracellular H(+)-activated cation channels family. Our previous studies suggested that ASIC1a contributed to acid-induced rat articular chondrocytes autophagy. However, its potential mechanisms remain unclear. The present study demonstrated t...

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Detalles Bibliográficos
Autores principales: Dai, Beibei, Zhu, Fei, Chen, Yong, Zhou, Renpeng, Wang, Zhisen, Xie, Yaya, Wu, Xiaoshan, Zu, Shengqin, Li, Ge, Ge, Jinfang, Chen, Feihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666807/
https://www.ncbi.nlm.nih.gov/pubmed/29019932
http://dx.doi.org/10.3390/ijms18102125