Cargando…

3,5,6,7,8,3′,4′-Heptamethoxyflavone Ameliorates Depressive-Like Behavior and Hippocampal Neurochemical Changes in Chronic Unpredictable Mild Stressed Mice by Regulating the Brain-Derived Neurotrophic Factor: Requirement for ERK Activation

We previously reported that the subcutaneous administration of 3,5,6,7,8,3′,4′-heptamethoxyflavone (HMF), a citrus polymethoxyflavone, attenuated depressive-like behavior and increased the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus of a corticosterone-induced depressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Sawamoto, Atsushi, Okuyama, Satoshi, Amakura, Yoshiaki, Yoshimura, Morio, Yamada, Takashi, Yokogoshi, Hidehiko, Nakajima, Mitsunari, Furukawa, Yoshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666815/
https://www.ncbi.nlm.nih.gov/pubmed/29023414
http://dx.doi.org/10.3390/ijms18102133