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Single Administration of Melatonin Modulates the Nitroxidergic System at the Peripheral Level and Reduces Thermal Nociceptive Hypersensitivity in Neuropathic Rats

Neuropathic pain is a severe condition with unsatisfactory treatments. Melatonin, an indolamine, seems to be a promising molecule suitable for this purpose due to its well-known anti-inflammatory, analgesic, and antioxidant effects, as well as its modulation of the nitroxidergic system. Nevertheless...

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Detalles Bibliográficos
Autores principales: Borsani, Elisa, Buffoli, Barbara, Bonazza, Veronica, Reiter, Russel J., Rezzani, Rita, Rodella, Luigi F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666825/
https://www.ncbi.nlm.nih.gov/pubmed/29036889
http://dx.doi.org/10.3390/ijms18102143