Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer

Epigenetic inactivation of tumor suppressor genes (TSG) is a fundamental event in the pathogenesis of human cancer. This silencing is accomplished by aberrant chromatin modifications including DNA hypermethylation of the gene promoter. One of the most frequently hypermethylated TSG in human cancer i...

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Detalles Bibliográficos
Autores principales: Dammann, Reinhard H., Richter, Antje M., Jiménez, Adriana P., Woods, Michelle, Küster, Miriam, Witharana, Chamindri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666841/
https://www.ncbi.nlm.nih.gov/pubmed/29039788
http://dx.doi.org/10.3390/ijms18102160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666841/
https://www.ncbi.nlm.nih.gov/pubmed/29039788
http://dx.doi.org/10.3390/ijms18102160

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