Seco-B-Ring Steroidal Dienynes with Aromatic D Ring: Design, Synthesis and Biological Evaluation

Continuing our structure-activity studies on the vitamin D analogs with the altered intercyclic seco-B-ring fragment, we designed compounds possessing dienyne system conjugated with the benzene D ring. Analysis of the literature data and the docking experiments seemed to indicate that the target com...

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Detalles Bibliográficos
Autores principales: Szybinski, Marcin, Brzeminski, Pawel, Fabisiak, Adrian, Berkowska, Klaudia, Marcinkowska, Ewa, Sicinski, Rafal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666843/
https://www.ncbi.nlm.nih.gov/pubmed/29039779
http://dx.doi.org/10.3390/ijms18102162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666843/
https://www.ncbi.nlm.nih.gov/pubmed/29039779
http://dx.doi.org/10.3390/ijms18102162

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