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Seco-B-Ring Steroidal Dienynes with Aromatic D Ring: Design, Synthesis and Biological Evaluation
Continuing our structure-activity studies on the vitamin D analogs with the altered intercyclic seco-B-ring fragment, we designed compounds possessing dienyne system conjugated with the benzene D ring. Analysis of the literature data and the docking experiments seemed to indicate that the target com...
Autores principales: | Szybinski, Marcin, Brzeminski, Pawel, Fabisiak, Adrian, Berkowska, Klaudia, Marcinkowska, Ewa, Sicinski, Rafal R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666843/ https://www.ncbi.nlm.nih.gov/pubmed/29039779 http://dx.doi.org/10.3390/ijms18102162 |
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