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Chronic Venous Insufficiency: Transforming Growth Factor-β Isoforms and Soluble Endoglin Concentration in Different States of Wound Healing

Venous leg ulcer (VLU) is a huge healthcare problem with poorly understood pathophysiology. Transforming growth factor-β (TGF-β) and endoglin (Eng), are inflammatory and wound healing mediators. Eng, co-receptor for TGF-β type-II receptors, may be cleaved forming soluble Eng (sEng), antagonizing TGF...

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Detalles Bibliográficos
Autores principales: Ligi, Daniela, Croce, Lidia, Mosti, Giovanni, Raffetto, Joseph D., Mannello, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666886/
https://www.ncbi.nlm.nih.gov/pubmed/29065449
http://dx.doi.org/10.3390/ijms18102206