Human Globozoospermia-Related Gene Spata16 Is Required for Sperm Formation Revealed by CRISPR/Cas9-Mediated Mouse Models

A recent genetic analysis of infertile globozoospermic patients identified causative mutations in three genes: a protein interacting with C kinase 1 (PICK1), dpy 19-like 2 (DPY19L2), and spermatogenesis associated 16 (SPATA16). Although mouse models have clarified the physiological functions of Pick...

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Detalles Bibliográficos
Autores principales: Fujihara, Yoshitaka, Oji, Asami, Larasati, Tamara, Kojima-Kita, Kanako, Ikawa, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666888/
https://www.ncbi.nlm.nih.gov/pubmed/29065458
http://dx.doi.org/10.3390/ijms18102208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666888/
https://www.ncbi.nlm.nih.gov/pubmed/29065458
http://dx.doi.org/10.3390/ijms18102208

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