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Coumestrol Epigenetically Suppresses Cancer Cell Proliferation: Coumestrol Is a Natural Haspin Kinase Inhibitor

Targeting epigenetic changes in gene expression in cancer cells may offer new strategies for the development of selective cancer therapies. In the present study, we investigated coumestrol, a natural compound exhibiting broad anti-cancer effects against skin melanoma, lung cancer and colon cancer ce...

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Detalles Bibliográficos
Autores principales: Kim, Jong-Eun, Lee, Sung-Young, Jang, Mi, Choi, Hyo-Kyung, Kim, Jong Hun, Chen, Hanyong, Lim, Tae-Gyu, Dong, Zigang, Lee, Ki Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666907/
https://www.ncbi.nlm.nih.gov/pubmed/29064398
http://dx.doi.org/10.3390/ijms18102228