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Selective Targeting of a Novel Vasodilator to the Uterine Vasculature to Treat Impaired Uteroplacental Perfusion in Pregnancy

Fetal growth restriction (FGR) in pregnancy is commonly caused by impaired uteroplacental blood flow. Vasodilators enhance uteroplacental perfusion and fetal growth in humans and animal models; however, detrimental maternal and fetal side effects have been reported. We hypothesised that targeted ute...

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Detalles Bibliográficos
Autores principales: Cureton, Natalie, Korotkova, Iana, Baker, Bernadette, Greenwood, Susan, Wareing, Mark, Kotamraju, Venkata R, Teesalu, Tambet, Cellesi, Francesco, Tirelli, Nicola, Ruoslahti, Erkki, Aplin, John D, Harris, Lynda K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667343/
https://www.ncbi.nlm.nih.gov/pubmed/29109771
http://dx.doi.org/10.7150/thno.19678