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Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes

Body fluids are a rich source of extracellular vesicles (EVs), which carry cargo derived from the secreting cells. So far, biomarkers for pathological conditions have been mainly searched from their protein, (mi)RNA, DNA and lipid cargo. Here, we explored the small molecule metabolites from urinary...

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Detalles Bibliográficos
Autores principales: Puhka, Maija, Takatalo, Maarit, Nordberg, Maria-Elisa, Valkonen, Sami, Nandania, Jatin, Aatonen, Maria, Yliperttula, Marjo, Laitinen, Saara, Velagapudi, Vidya, Mirtti, Tuomas, Kallioniemi, Olli, Rannikko, Antti, Siljander, Pia R-M, af Hällström, Taija Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667407/
https://www.ncbi.nlm.nih.gov/pubmed/29109780
http://dx.doi.org/10.7150/thno.19890