Limitations of lymphoblastoid cell lines for functional analysis of SNPs

OBJECTIVE: Single nucleotide polymorphisms (SNPs) are widely linked to the susceptibility and penetrance of diseases. SNP rs886205 (A/G) located in the aldehyde dehydrogenase 2 (ALDH2) promoter is associated with esophageal carcinoma in alcohol-dependent patients. Previously, we found an interaction...

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Detalles Bibliográficos
Autores principales: Pathak, Hansi, Frieling, Helge, Rhein, Mathias, Burkert, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667475/
https://www.ncbi.nlm.nih.gov/pubmed/29096698
http://dx.doi.org/10.1186/s13104-017-2864-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667475/
https://www.ncbi.nlm.nih.gov/pubmed/29096698
http://dx.doi.org/10.1186/s13104-017-2864-6

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