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14-3-3ζ loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature

BACKGROUND: The 14-3-3 family of proteins have been reported to play an important role in development in various mouse models, but the context specific developmental functions of 14-3-3ζ remain to be determined. In this study, we identified a context specific developmental function of 14-3-3ζ. RESUL...

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Detalles Bibliográficos
Autores principales: Yang, Jun, Joshi, Sonali, Wang, Qingfei, Li, Ping, Wang, Hai, Xiong, Yan, Xiao, Yi, Wang, Jinyang, Parker-Thornburg, Jan, Behringer, Richard R., Yu, Dihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667492/
https://www.ncbi.nlm.nih.gov/pubmed/29118970
http://dx.doi.org/10.1186/s13578-017-0186-y