Cargando…

A novel (18)F-labelled high affinity agent for PET imaging of the translocator protein

The translocator protein (TSPO) is an important target for imaging focal neuroinflammation in diseases such as brain cancer, stroke and neurodegeneration, but current tracers for non-invasive imaging of TSPO have important limitations. We present the synthesis and evaluation of a novel 3-fluoromethy...

Descripción completa

Detalles Bibliográficos
Autores principales: Blair, Adele, Zmuda, Filip, Malviya, Gaurav, Tavares, Adriana A. S., Tamagnan, Gilles D., Chalmers, Anthony J., Dewar, Deborah, Pimlott, Sally L., Sutherland, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667507/
https://www.ncbi.nlm.nih.gov/pubmed/29142713
http://dx.doi.org/10.1039/c5sc01647a