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Integrating proteomics with electrochemistry for identifying kinase biomarkers

We present an integrated approach for highly sensitive identification and validation of substrate-specific kinases as cancer biomarkers. Our approach combines phosphoproteomics for high throughput cancer-related biomarker discovery from patient tissues and an impedimetric kinase activity biosensor f...

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Detalles Bibliográficos
Autores principales: Amit, Einav, Obena, Rofeamor, Wang, Yi-Ting, Zhuravel, Roman, Reyes, Aaron James F., Elbaz, Shir, Rotem, Dvir, Porath, Danny, Friedler, Assaf, Chen, Yu-Ju, Yitzchaik, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667508/
https://www.ncbi.nlm.nih.gov/pubmed/29142712
http://dx.doi.org/10.1039/c5sc00560d