Endoplasmic reticulum stress inhibits expression of genes involved in thyroid hormone synthesis and their key transcriptional regulators in FRTL-5 thyrocytes

Endoplasmic reticulum (ER) stress is characterized by the accumulation of misfolded proteins due to an impairment of ER quality control pathways leading to the activation of a defense system, called unfolded protein response (UPR). While thyrocytes are supposed to be highly susceptible to environmen...

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Detalles Bibliográficos
Autores principales: Wen, Gaiping, Ringseis, Robert, Eder, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667865/
https://www.ncbi.nlm.nih.gov/pubmed/29095946
http://dx.doi.org/10.1371/journal.pone.0187561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667865/
https://www.ncbi.nlm.nih.gov/pubmed/29095946
http://dx.doi.org/10.1371/journal.pone.0187561

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