A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine

The effectiveness of the annual influenza vaccine has declined in recent years, especially for the H3N2 component, and is a concern for global public health. A major cause for this lack in effectiveness has been attributed to the egg-based vaccine production process. Substitutions on the hemagglutin...

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Detalles Bibliográficos
Autores principales: Wu, Nicholas C., Zost, Seth J., Thompson, Andrew J., Oyen, David, Nycholat, Corwin M., McBride, Ryan, Paulson, James C., Hensley, Scott E., Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667890/
https://www.ncbi.nlm.nih.gov/pubmed/29059230
http://dx.doi.org/10.1371/journal.ppat.1006682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667890/
https://www.ncbi.nlm.nih.gov/pubmed/29059230
http://dx.doi.org/10.1371/journal.ppat.1006682

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