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Diverse type 2 diabetes genetic risk factors functionally converge in a phenotype-focused gene network

Type 2 Diabetes (T2D) constitutes a global health burden. Efforts to uncover predisposing genetic variation have been considerable, yet detailed knowledge of the underlying pathogenesis remains poor. Here, we constructed a T2D phenotypic-linkage network (T2D-PLN), by integrating diverse gene functio...

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Detalles Bibliográficos
Autores principales: Sandor, Cynthia, Beer, Nicola L., Webber, Caleb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667928/
https://www.ncbi.nlm.nih.gov/pubmed/29059180
http://dx.doi.org/10.1371/journal.pcbi.1005816