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Combinatorial action of Grainyhead, Extradenticle and Notch in regulating Hox mediated apoptosis in Drosophila larval CNS

Hox mediated neuroblast apoptosis is a prevalent way to pattern larval central nervous system (CNS) by different Hox genes, but the mechanism of this apoptosis is not understood. Our studies with Abdominal-A (Abd-A) mediated larval neuroblast (pNB) apoptosis suggests that AbdA, its cofactor Extraden...

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Detalles Bibliográficos
Autores principales: Khandelwal, Risha, Sipani, Rashmi, Govinda Rajan, Sriivatsan, Kumar, Raviranjan, Joshi, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667929/
https://www.ncbi.nlm.nih.gov/pubmed/29023471
http://dx.doi.org/10.1371/journal.pgen.1007043