A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

Epidermal homeostasis depends on a balance between stem cell renewal and terminal differentiation. The transition between the two cell states, termed commitment, is poorly understood. Here, we characterise commitment by integrating transcriptomic and proteomic data from disaggregated primary human k...

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Detalles Bibliográficos
Autores principales: Mishra, Ajay, Oulès, Bénédicte, Pisco, Angela Oliveira, Ly, Tony, Liakath-Ali, Kifayathullah, Walko, Gernot, Viswanathan, Priyalakshmi, Tihy, Matthieu, Nijjher, Jagdeesh, Dunn, Sara-Jane, Lamond, Angus I, Watt, Fiona M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667932/
https://www.ncbi.nlm.nih.gov/pubmed/29043977
http://dx.doi.org/10.7554/eLife.27356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667932/
https://www.ncbi.nlm.nih.gov/pubmed/29043977
http://dx.doi.org/10.7554/eLife.27356

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