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A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis
Epidermal homeostasis depends on a balance between stem cell renewal and terminal differentiation. The transition between the two cell states, termed commitment, is poorly understood. Here, we characterise commitment by integrating transcriptomic and proteomic data from disaggregated primary human k...
Autores principales: | Mishra, Ajay, Oulès, Bénédicte, Pisco, Angela Oliveira, Ly, Tony, Liakath-Ali, Kifayathullah, Walko, Gernot, Viswanathan, Priyalakshmi, Tihy, Matthieu, Nijjher, Jagdeesh, Dunn, Sara-Jane, Lamond, Angus I, Watt, Fiona M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667932/ https://www.ncbi.nlm.nih.gov/pubmed/29043977 http://dx.doi.org/10.7554/eLife.27356 |
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