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The impacts of genetic polymorphisms in genes of base excision repair pathway on the efficacy and acute toxicities of (chemo)radiotherapy in patients with nasopharyngeal carcinoma

PURPOSE: To explore whether polymorphisms in base excision repair (BER) pathway genes are predictors of (chemo)radiotherapy outcome in patients with nasopharyngeal carcinoma (NPC). METHODS: We genotyped five potentially functional single nucleotide polymorphisms (SNPs) of three genes in the BER path...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Guo, Chengxian, Gong, Xiaochang, Ao, Fan, Huang, Yuling, Huang, Lihua, Tang, Yiqiang, Jiang, Chunling, Xie, Xiaoxue, Dong, Qing, Huang, Min, Li, Jingao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667987/
https://www.ncbi.nlm.nih.gov/pubmed/29108254
http://dx.doi.org/10.18632/oncotarget.20203