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Regulation of neuroinflammation by matrix metalloproteinase-8 inhibitor derivatives in activated microglia and astrocytes

Matrix metalloproteinases (MMPs) play a pivotal role in neuroinflammation that is associated with neurodegenerative diseases. Our group recently reported that MMP-8 mediates inflammatory reactions by modulating the processing of TNF-α. To improve the efficacy of the currently available MMP-8 inhibit...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Jung, Choi, Min-Ji, Lee, Gyeongjin, Gaire, Bhakta Prasad, Choi, Ji Woong, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667990/
https://www.ncbi.nlm.nih.gov/pubmed/29108257
http://dx.doi.org/10.18632/oncotarget.20207