Beta-catenin represses protein kinase D1 gene expression by non-canonical pathway through MYC/MAX transcription complex in prostate cancer

Down regulation of Protein Kinase D1 (PrKD1), a novel serine threonine kinase, in prostate, gastric, breast and colon cancers in humans leads to disease progression. While the down regulation of PrKD1 by DNA methylation in gastric cancer and by nuclear beta-catenin in colon cancer has been shown, th...

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Detalles Bibliográficos
Autores principales: Nickkholgh, Bita, Sittadjody, Sivanandane, Rothberg, Michael B., Fang, Xiaolan, Li, Kunzhao, Chou, Jeff W., Hawkins, Gregory A., Balaji, K.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668000/
https://www.ncbi.nlm.nih.gov/pubmed/29108267
http://dx.doi.org/10.18632/oncotarget.20229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668000/
https://www.ncbi.nlm.nih.gov/pubmed/29108267
http://dx.doi.org/10.18632/oncotarget.20229

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