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Beta-catenin represses protein kinase D1 gene expression by non-canonical pathway through MYC/MAX transcription complex in prostate cancer
Down regulation of Protein Kinase D1 (PrKD1), a novel serine threonine kinase, in prostate, gastric, breast and colon cancers in humans leads to disease progression. While the down regulation of PrKD1 by DNA methylation in gastric cancer and by nuclear beta-catenin in colon cancer has been shown, th...
Autores principales: | Nickkholgh, Bita, Sittadjody, Sivanandane, Rothberg, Michael B., Fang, Xiaolan, Li, Kunzhao, Chou, Jeff W., Hawkins, Gregory A., Balaji, K.C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668000/ https://www.ncbi.nlm.nih.gov/pubmed/29108267 http://dx.doi.org/10.18632/oncotarget.20229 |
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