Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma

BACKGROUND: Currently mainly BRAF mutant circulating tumor DNA (ctDNA) is utilized to monitor patients with melanoma. TERT promoter mutations are common in various cancers and found in up to 70% of melanomas, including half of BRAF wild-type cases. Therefore, a sensitive method for detection of TERT...

Descripción completa

Detalles Bibliográficos
Autores principales: McEvoy, Ashleigh C., Calapre, Leslie, Pereira, Michelle R., Giardina, Tindaro, Robinson, Cleo, Khattak, Muhammad A., Meniawy, Tarek M., Pritchard, Antonia L., Hayward, Nicholas K., Amanuel, Benhur, Millward, Michael, Ziman, Melanie, Gray, Elin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668006/
https://www.ncbi.nlm.nih.gov/pubmed/29108273
http://dx.doi.org/10.18632/oncotarget.20354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668006/
https://www.ncbi.nlm.nih.gov/pubmed/29108273
http://dx.doi.org/10.18632/oncotarget.20354

Ejemplares similares