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Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma
BACKGROUND: Currently mainly BRAF mutant circulating tumor DNA (ctDNA) is utilized to monitor patients with melanoma. TERT promoter mutations are common in various cancers and found in up to 70% of melanomas, including half of BRAF wild-type cases. Therefore, a sensitive method for detection of TERT...
Autores principales: | McEvoy, Ashleigh C., Calapre, Leslie, Pereira, Michelle R., Giardina, Tindaro, Robinson, Cleo, Khattak, Muhammad A., Meniawy, Tarek M., Pritchard, Antonia L., Hayward, Nicholas K., Amanuel, Benhur, Millward, Michael, Ziman, Melanie, Gray, Elin S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668006/ https://www.ncbi.nlm.nih.gov/pubmed/29108273 http://dx.doi.org/10.18632/oncotarget.20354 |
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