Cargando…

A Relationship between the aldosterone - mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans

Aldosterone regulates electrolyte and fluid homeostasis through binding to the mineralocorticoid receptors (MR). Previous work provides evidence for a role of aldosterone in alcohol use disorders (AUD). We tested the hypothesis that high functional activity of the mineralocorticoid endocrine pathway...

Descripción completa

Detalles Bibliográficos
Autores principales: Aoun, E.G., Jimenez, V.A., Vendruscolo, L.F., Walter, N.A.R., Barbier, E., Ferrulli, A., Haass-Koffler, C. L., Darakjian, P., Lee, M.R., Addolorato, G., Heilig, M., Hitzemann, R., Koob, G.F., Grant, K.A., Leggio, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668213/
https://www.ncbi.nlm.nih.gov/pubmed/28461696
http://dx.doi.org/10.1038/mp.2017.97