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Efficacy of an Adenoviral Vectored Multivalent Centralized Influenza Vaccine

Mice were immunized with Adenovirus expressing the H1-con, H2-con, H3-con and H5-con HA consensus genes in combination (multivalent) and compared to mice immunized with the traditional 2010–2011 FluZone and FluMist seasonal vaccines. Immunized mice were challenged with 10–100 MLD(50) of H1N1, H3N1,...

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Detalles Bibliográficos
Autores principales: Lingel, Amy, Bullard, Brianna L., Weaver, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668234/
https://www.ncbi.nlm.nih.gov/pubmed/29097763
http://dx.doi.org/10.1038/s41598-017-14891-y