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Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs

The Drosophila Hedgehog receptor functions to regulate the essential downstream pathway component, Smoothened, and to limit the range of signaling by sequestering Hedgehog protein signal within imaginal disc epithelium. Hedgehog receptor function requires both Patched and Ihog activity, the latter i...

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Detalles Bibliográficos
Autores principales: Hsia, Elaine Y. C., Zhang, Ya, Tran, Hai Son, Lim, Agnes, Chou, Ya-Hui, Lan, Ganhui, Beachy, Philip A., Zheng, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668237/
https://www.ncbi.nlm.nih.gov/pubmed/29097673
http://dx.doi.org/10.1038/s41467-017-01364-z