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Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs
The Drosophila Hedgehog receptor functions to regulate the essential downstream pathway component, Smoothened, and to limit the range of signaling by sequestering Hedgehog protein signal within imaginal disc epithelium. Hedgehog receptor function requires both Patched and Ihog activity, the latter i...
Autores principales: | Hsia, Elaine Y. C., Zhang, Ya, Tran, Hai Son, Lim, Agnes, Chou, Ya-Hui, Lan, Ganhui, Beachy, Philip A., Zheng, Xiaoyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668237/ https://www.ncbi.nlm.nih.gov/pubmed/29097673 http://dx.doi.org/10.1038/s41467-017-01364-z |
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