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Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101

The increasing frequency of antimicrobial resistance is a problem of global importance. Novel strategies are urgently needed to understand and inhibit antimicrobial resistance gene transmission that is mechanistically related to bacterial virulence functions. The conjugative transfer of plasmids by...

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Detalles Bibliográficos
Autores principales: Casu, Bastien, Arya, Tarun, Bessette, Benoit, Baron, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668240/
https://www.ncbi.nlm.nih.gov/pubmed/29097752
http://dx.doi.org/10.1038/s41598-017-14953-1