Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork

Increased synthesis and deposition of extracellular matrix (ECM) proteins in the trabecular meshwork (TM) is associated with TM dysfunction and intraocular pressure (IOP) elevation in glaucoma. However, it is not understood how ECM accumulation leads to TM dysfunction and IOP elevation. Using a mous...

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Detalles Bibliográficos
Autores principales: Kasetti, Ramesh B., Maddineni, Prabhavathi, Millar, J. Cameron, Clark, Abbot F., Zode, Gulab S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668243/
https://www.ncbi.nlm.nih.gov/pubmed/29097767
http://dx.doi.org/10.1038/s41598-017-14938-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668243/
https://www.ncbi.nlm.nih.gov/pubmed/29097767
http://dx.doi.org/10.1038/s41598-017-14938-0

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