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Identification of pharmacological agents that induce HMGB1 release

The translocation of the protein high mobility group box 1 (HMGB1) from the nucleus to the cytoplasm and its secretion or passive release through the permeabilized plasma membrane, constitutes a major cellular danger signal. Extracellular HMGB1 can interact with pattern recognition receptors to stim...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Zhao, Liwei, Loos, Friedemann, Iribarren, Kristina, Lachkar, Sylvie, Zhou, Heng, Gomes-da-Silva, Lígia C., Chen, Guo, Bezu, Lucillia, Boncompain, Gaelle, Perez, Franck, Zitvogel, Laurence, Kepp, Oliver, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668281/
https://www.ncbi.nlm.nih.gov/pubmed/29097772
http://dx.doi.org/10.1038/s41598-017-14848-1