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Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain

The induction of antibodies specific for the influenza HA protein stalk domain is being pursued as a universal strategy against influenza virus infections. However, little work has been done looking at natural or induced antigenic variability in this domain and the effects on viral fitness. We analy...

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Detalles Bibliográficos
Autores principales: Anderson, Christopher S., Ortega, Sandra, Chaves, Francisco A., Clark, Amelia M., Yang, Hongmei, Topham, David J., DeDiego, Marta L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668287/
https://www.ncbi.nlm.nih.gov/pubmed/29097696
http://dx.doi.org/10.1038/s41598-017-14931-7