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Heparanase and macrophage interplay in the onset of liver fibrosis

The heparan sulfate endoglycosidase heparanase (HPSE) is involved in tumor growth, chronic inflammation and fibrosis. Since a role for HPSE in chronic liver disease has not been demonstrated to date, the current study was aimed at investigating the involvement of HPSE in the pathogenesis of chronic...

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Detalles Bibliográficos
Autores principales: Secchi, Maria Francesca, Crescenzi, Marika, Masola, Valentina, Russo, Francesco Paolo, Floreani, Annarosa, Onisto, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668295/
https://www.ncbi.nlm.nih.gov/pubmed/29097791
http://dx.doi.org/10.1038/s41598-017-14946-0