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Disease-relevant signalling-pathways in head and neck cancer: Taspase1’s proteolytic activity fine-tunes TFIIA function

Head and neck cancer (HNC) is the seventh most common malignancy in the world and its prevailing form, the head and neck squamous cell carcinoma (HNSCC), is characterized as aggressive and invasive cancer type. The transcription factor II A (TFIIA), initially described as general regulator of RNA po...

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Detalles Bibliográficos
Autores principales: Gribko, Alena, Hahlbrock, Angelina, Strieth, Sebastian, Becker, Sven, Hagemann, Jan, Deichelbohrer, Max, Hildebrandt, Andreas, Habtemichael, Negusse, Wünsch, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668323/
https://www.ncbi.nlm.nih.gov/pubmed/29097782
http://dx.doi.org/10.1038/s41598-017-14814-x