NMD monitors translational fidelity 24/7

Nonsense-mediated mRNA decay (NMD) is generally thought to be a eukaryotic mRNA surveillance pathway tasked with the elimination of transcripts harboring an in-frame premature termination codon (PTC). As presently conceived, NMD acting in this manner minimizes the likelihood that potentially toxic p...

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Detalles Bibliográficos
Autores principales: Celik, Alper, He, Feng, Jacobson, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668330/
https://www.ncbi.nlm.nih.gov/pubmed/28536849
http://dx.doi.org/10.1007/s00294-017-0709-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668330/
https://www.ncbi.nlm.nih.gov/pubmed/28536849
http://dx.doi.org/10.1007/s00294-017-0709-4

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