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NMD monitors translational fidelity 24/7
Nonsense-mediated mRNA decay (NMD) is generally thought to be a eukaryotic mRNA surveillance pathway tasked with the elimination of transcripts harboring an in-frame premature termination codon (PTC). As presently conceived, NMD acting in this manner minimizes the likelihood that potentially toxic p...
Autores principales: | Celik, Alper, He, Feng, Jacobson, Allan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668330/ https://www.ncbi.nlm.nih.gov/pubmed/28536849 http://dx.doi.org/10.1007/s00294-017-0709-4 |
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