IPET study: an FLT-PET window study to assess the activity of the steroid sulfatase inhibitor irosustat in early breast cancer

BACKGROUND: Steroid sulfatase (STS) is involved in oestrogen biosynthesis and irosustat is a first generation, irreversible steroid sulfatase inhibitor. A pre-surgical window-of-opportunity study with irosustat was undertaken in estrogen receptor-positive (ER+) breast cancer to assess the effect of...

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Detalles Bibliográficos
Autores principales: Palmieri, Carlo, Szydlo, Richard, Miller, Marie, Barker, Laura, Patel, Neva H., Sasano, Hironobu, Barwick, Tara, Tam, Henry, Hadjiminas, Dimitri, Lee, Jasmin, Shaaban, Abeer, Nicholas, Hanna, Coombes, R. Charles, Kenny, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668341/
https://www.ncbi.nlm.nih.gov/pubmed/28795252
http://dx.doi.org/10.1007/s10549-017-4427-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668341/
https://www.ncbi.nlm.nih.gov/pubmed/28795252
http://dx.doi.org/10.1007/s10549-017-4427-x

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