Pharmacologically induced reversible hypometabolic state mitigates radiation induced lethality in mice

Therapeutic hypothermia has proven benefits in critical care of a number of diseased states, where inflammation and oxidative stress are the key players. Here, we report that adenosine monophosphate (AMP) triggered hypometabolic state (HMS), 1–3 hours after lethal total body irradiation (TBI) for a...

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Detalles Bibliográficos
Autores principales: Ghosh, Subhajit, Indracanti, Namita, Joshi, Jayadev, Ray, Jharna, Indraganti, Prem Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668348/
https://www.ncbi.nlm.nih.gov/pubmed/29097738
http://dx.doi.org/10.1038/s41598-017-15002-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668348/
https://www.ncbi.nlm.nih.gov/pubmed/29097738
http://dx.doi.org/10.1038/s41598-017-15002-7

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