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Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling

Thrombopoietin (TPO) is the master cytokine regulator of megakaryopoiesis. In addition to regulation of megakaryocyte and platelet number, TPO is important for maintaining proper hematopoietic stem cell (HSC) function. It was previously shown that a number of lymphoid genes were upregulated in HSCs...

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Detalles Bibliográficos
Autores principales: Au, Amanda E., Lebois, Marion, Sim, Starling A., Cannon, Ping, Corbin, Jason, Gangatirkar, Pradnya, Hyland, Craig D., Moujalled, Diane, Rutgersson, Angelika, Yassinson, Fatme, Kile, Benjamin T., Mason, Kylie D., Ng, Ashley P., Alexander, Warren S., Josefsson, Emma C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668349/
https://www.ncbi.nlm.nih.gov/pubmed/29097774
http://dx.doi.org/10.1038/s41598-017-15023-2