A model integrating tonic and antigen-triggered BCR signals to predict the survival of primary B cells

The BCR constitutively transmits a “tonic” survival signal in the absence of exogenous antigen-binding. However, the strength of tonic BCR signal and its relationship with antigen-triggered survival signal are poorly understood. We found that primary B cells expressing high levels of BCR had elevate...

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Detalles Bibliográficos
Autores principales: Yasuda, Shoya, Zhou, Yang, Wang, Yanqing, Yamamura, Masayuki, Wang, Ji-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668375/
https://www.ncbi.nlm.nih.gov/pubmed/29097663
http://dx.doi.org/10.1038/s41598-017-13993-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668375/
https://www.ncbi.nlm.nih.gov/pubmed/29097663
http://dx.doi.org/10.1038/s41598-017-13993-x

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