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A model integrating tonic and antigen-triggered BCR signals to predict the survival of primary B cells
The BCR constitutively transmits a “tonic” survival signal in the absence of exogenous antigen-binding. However, the strength of tonic BCR signal and its relationship with antigen-triggered survival signal are poorly understood. We found that primary B cells expressing high levels of BCR had elevate...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668375/ https://www.ncbi.nlm.nih.gov/pubmed/29097663 http://dx.doi.org/10.1038/s41598-017-13993-x |