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Iron deposition in substantia nigra: abnormal iron metabolism, neuroinflammatory mechanism and clinical relevance

Parkinson disease (PD) is associated with multiple factors, including iron, which is demonstrated to deposit excessively in PD brains. We detected iron deposition by susceptibility weighted image (SWI) and measured the levels of iron metabolism-related proteins and inflammatory factors in cerebrospi...

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Detalles Bibliográficos
Autores principales: Liu, Zhuo, Shen, Hui-cong, Lian, Teng-hong, Mao, Lei, Tang, Shou-xian, Sun, Li, Huang, Xi-yan, Guo, Peng, Cao, Chen-jie, Yu, Shu-yang, Zuo, Li-jun, Wang, Xiao-Min, Chen, Sheng-Di, Chan, Piu, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668412/
https://www.ncbi.nlm.nih.gov/pubmed/29097764
http://dx.doi.org/10.1038/s41598-017-14721-1