Advanced glycation end products promote VEGF expression and thus choroidal neovascularization via Cyr61-PI3K/AKT signaling pathway

Choroidal neovascularisation (CNV) causes severe vision loss among old patients, especially those with diabetes. Previously, Cyr61 has been found to play a critical role in the pathogenesis of both AMD and diabetes. In the present study, we found that increased CNV severity together with higher expr...

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Detalles Bibliográficos
Autores principales: Sun, Lijuan, Huang, Tonglie, Xu, Wenqin, Sun, Jiaxing, Lv, Yang, Wang, Yusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668426/
https://www.ncbi.nlm.nih.gov/pubmed/29097668
http://dx.doi.org/10.1038/s41598-017-14015-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668426/
https://www.ncbi.nlm.nih.gov/pubmed/29097668
http://dx.doi.org/10.1038/s41598-017-14015-6

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