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Specific and intrinsic sequence patterns extracted by deep learning from intra-protein binding and non-binding peptide fragments

The key finding in the DNA double helix model is the specific pairing or binding between nucleotides A-T and C-G, and the pairing rules are the molecule basis of genetic code. Unfortunately, no such rules have been discovered for proteins. Here we show that intrinsic sequence patterns between intra-...

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Detalles Bibliográficos
Autores principales: Wang, Yuhong, Huang, Junzhou, Li, Wei, Wang, Sheng, Ding, Chuanfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668431/
https://www.ncbi.nlm.nih.gov/pubmed/29097708
http://dx.doi.org/10.1038/s41598-017-14877-w