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Ctbp2-mediated β-catenin regulation is required for exit from pluripotency

The canonical Wnt pathway is critical for embryonic stem cell (ESC) pluripotency and aberrant control of β-catenin leads to failure of exit from pluripotency and lineage commitments. Hence, maintaining the appropriate level of β-catenin is important for the decision to commit to the appropriate line...

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Detalles Bibliográficos
Autores principales: Kim, Tae Wan, Kwak, Sojung, Shin, Jihoon, Kang, Byung-Hee, Lee, Sang-Eun, Suh, Min Young, Kim, Jae-Hwan, Hwang, In-Young, Lee, Jong-Hyuk, Choi, Jinmi, Cho, Eun-Jung, Youn, Hong-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668466/
https://www.ncbi.nlm.nih.gov/pubmed/29026198
http://dx.doi.org/10.1038/emm.2017.147