Model structures of inactive and peptide agonist bound C5aR: Insights into agonist binding, selectivity and activation

C5a receptor (C5aR) is one of the major chemoattractant receptors of the druggable proteome that binds C5a, the proinflammatory polypeptide of complement cascade, triggering inflammation and SEPSIS. Here, we report the model structures of C5aR in both inactive and peptide agonist (YSFKPMPLaR; a=D-Al...

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Detalles Bibliográficos
Autores principales: Rana, Soumendra, Sahoo, Amita Rani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668562/
https://www.ncbi.nlm.nih.gov/pubmed/29124137
http://dx.doi.org/10.1016/j.bbrep.2015.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668562/
https://www.ncbi.nlm.nih.gov/pubmed/29124137
http://dx.doi.org/10.1016/j.bbrep.2015.03.002

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